The Commission discusses the range of medical imaging modalities, interventional radiology, and radionuclide therapies used today and the stark contrast in their availability in different countries around the world. It also plays key roles throughout the cancer care continuum, including in tumour staging, treatment planning and targeting, monitoring tumour response, and in patient follow-up and detection of relapse. Medical imaging is often a neglected topic in global oncology guidelines, but is crucial in cancer care, since imaging is essential to diagnose-or exclude-both adult and childhood cancers, and both solid and haematological malignancies. The Lancet Oncology Commission on medical imaging and nuclear medicine highlights the need to improve awareness of and patient access to affordable and effective cancer imaging worldwide. Ultimately, political will and effective collaboration between multiple stakeholders is needed to reach the achievable goal of improved cancer care in sub-Saharan Africa. In this Commission, the authors describe these challenges in detail, and propose actions that must be taken urgently to address the escalating catastrophe. However, the fragile health systems in the 46 sub-Saharan African nations are poorly equipped to tackle this looming health crisis, with many problems including incomplete cancer data registries, poor availability of and access to screening, diagnostics, and treatment, insufficient provision of palliative care, and a huge shortfall of trained medical personnel compounding the deteriorating situation. Long affected by infectious diseases and malnutrition, the population of this region is now increasingly afflicted by non-communicable diseases, including cancer. The Lancet Oncology Commission on cancer in sub-Saharan Africa highlights the rapidly escalating cancer burden in this resource-poor area of the world. Development of evidence-based recommendations to accelerate innovation remains a crucial aspect of clinical practice and research in this area. In the second paper, Maria Kyrgiou and colleagues present the 2022 consensus recommendations on the terminology for cone dimensions after local conservative treatment for cervical intraepithelial neoplasia and early invasive cervical cancer from the European Society of Gynaecologic Oncology, the European Federation for Colposcopy, the International Federation of Cervical Pathology and Colposcopy, and the European Society of Pathology. In the first paper in this Series, Ignace Vergote and colleagues present the consensus recommendations from the sixth Gynecologic Cancer InterGroup (GCIG) Ovarian Cancer Consensus Conference on Clinical Research. In view of the prevalence of gynaecological cancers and the substantial burden these diseases have on women around the world, coordinated efforts are still very much needed to optimise treatments for these cancers. The Lancet Regional Health – Western Pacific.The Lancet Regional Health – Southeast Asia.The Lancet Gastroenterology & Hepatology.
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